Cook the protein macaroni in a large pot of salted boiling water according to package directions until al dente; drain and set aside.
In a large non-stick skillet over medium-high heat, brown the lean ground beef until fully cooked, breaking it into small crumbles. Drain any excess fat.
Add the diced green bell pepper and yellow onion to the skillet with the beef and sauté for 5 to 7 minutes until the vegetables are softened.
Stir in the garlic powder, onion powder, sea salt, black pepper, and Worcestershire sauce to season the beef mixture.
Reduce the skillet heat to low. Whisk in the skim milk and fat-free Greek yogurt, stirring constantly to prevent curdling.
Gradually fold in the shredded provolone cheese, stirring until the cheese is completely melted and the sauce is smooth and creamy.
Add the cooked macaroni to the skillet and toss thoroughly until the pasta is evenly coated in the cheese and beef mixture.
Remove from heat and serve immediately while the sauce is at peak creaminess.